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ea0019p44 | Clinical practice/governance and case reports | SFEBES2009

Lessons from a case of pituitary thyrotrophinoma I: not all TSH-omas are macroadenomas II: thyroid autoimmunity can be associated III: associated central hyperthyroidism can be subclinical

Arutchelvam V , Neely RDG , Mitra D , Hill J , Carrie S , Gurnell M , Quinton R

A 64-year-old lady presented with weight gain, tiredness, palpitations and tremor. She had no goitre and no other extra thyroidal manifestations. Both TSH and thyroid peroxidase antibodies (>1300) were elevated and she was treated by her GP with Thyroxine 50 mcg daily. She felt a lot worse on this, so it was discontinued and a full thyroid hormone profile was checked (see Table 1) which prompted referral; to Endocrinology.Other pituitary hormone leve...

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ea0013p220 | AMEND Young Investigator's Award | SFEBES2007

Diagnosing early acromegaly: the pre-test probability of disease is strongly influenced by the presence or absence of other associated diseases

Bhattacharya Beas , Syed Akheel , Razvi Salmon , Johnson K , Hill J , Carrie S , Mitra D , Quinton Richard

A 44-year-old man referred with erectile dysfunction was found to have hypogonadotrophic hypogonadism (HH), but otherwise apparently normal anterior pituitary function (LH 1.6 & FSH 2.7 IU/l; T 3.4 & cortisol 516 nmol/l; PRL 103, GH 5.5 & TSH 2.8 mU/l; f-T4 13, f-T3 4.8 & f-T 128 pmol/l; ferritin 103 ug/l). He appeared normally virilised, with central obesity (BMI 36 kg.m−2, collar size 46 cm) and symptomatic sleep apnoea (SA). MRI showed a rig...

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Endocrine Abstracts

Lessons from a case of pituitary thyrotrophinoma I: not all TSH-omas are macroadenomas II: thyroid autoimmunity can be associated III: associated central hyperthyroidism can be subclinical

Diagnosing early acromegaly: the pre-test probability of disease is strongly influenced by the presence or absence of other associated diseases

BiosciAbstracts